PHA 060 LAS 1-4 QUIZ (AY 2526)
Question 1
A poison is BEST defined as a substance that:
Causes allergic reactions only
Produces toxicity or death when introduced into the body
Is harmful only at high doses
Is always synthetic
Question 2
What is the significance of ED₅₀ in toxicology?
It is the dose that produces therapeutic effects in half the test subjects
It is the dose that kills 100% of animals
It measures solubility of a poison
It refers to an allergic threshold dose
Question 3
The term dose refers to:
Duration of exposure
Frequency of administration
Amount of substance entering the body at one time
Concentration in blood
Question 4
The therapeutic index is calculated by which of the following formulas?
ED₅₀/LD₅₀
LD₅₀/ED₅₀
NOEL/ED₅₀
TD₅₀/LD₅₀
Question 5
What principle did Paracelsus establish?
Toxins are harmless below threshold
The dose makes the poison
Only natural poisons are dangerous
Humans are resistant to chemical exposure
Question 6
This toxicant binds to hemoglobin with high affinity that leads to carboxyhemoglobin formation which eventually causes tissue hypoxia:
Malathion
Carbon dioxide
Carbon monoxide
Two of the choices
Question 7
A toxic substance produced by fungi is classified as a:
Toxin
Toxicant
Carcinogen
Irritant
Question 8
An allergic reaction triggered by a small molecule binding to a host protein is known as:
Chemical idiosyncrasy
Delayed toxicity
Hapten-mediated allergy
Local irritation
Question 9
If an agent is known to cause developmental defects it is called a mutagen. An example of such is Thalidomide.
First statement is correct. Second statement is incorrect.
First statement is incorrect. Second statement is correct.
Both statements are correct.
Both statements are incorrect.
Question 10
Evaluate which of the following is/are TRUE regarding Aflatoxin:
I. Derived from Aspergillus flavus
II. Common in contaminated grains and nuts.
III. Hepatotoxic and carcinogenic
One statement is correct.
Two statements are correct.
Three statements are correct.
All of the statements are incorrect.
Question 11
Which of the following is most associated with needle marks as a dermal sign of chronic poisoning?
Arsenic
Bromides
Heroin
Datura
Question 12
What is the most rapid route of toxin absorption?
Inhalation
Intravenous
Oral
Dermal
Question 13
Which chemical causes profuse sweating during acute exposure?
Arsenic
Morphine
Bromides
Clonidine
Question 14
What pharmacodynamic interaction is seen when you combined caffeine and taurine?
Potentiation
Synergism
Antagonism
Additive
Question 15
What specific color does Aniline pose as an oil?
Red
Orange
Blue
Green
Question 16
This household intoxicant has a density of 0.791g/mL and becomes a CNS depressant at high levels.
Sodium hypochlorite
Carbon disulfide
Aniline
Acetone
Question 17
Positive result of Lead acetate test is:
Flesh colored ppt of tribromoaniline
Black precipitate with hydrochloric acid
Black zone
Heavy purple mass
Question 18
Which of the following is NOT an acute S&Sx of acetone toxicity:
Sweet taste in mouth
Lethargy
Ketoacidosis
Slurred speech
Question 19
Minimum fatal dose of Aniline?
5mg
0.05g
500mg
50g
Question 20
Repulsive odor is a positive result of which test?
Reynold’s Test
Benzoldt test
Phenylisocyanide test
Ferric chloride test
Question 21
It is a colorless inflammable liquid, with a characteristic odor which approximately boils at 42°C, and a high index of refraction.
Carbon disulfide
Acetone
Aniline
Propoxur
Question 22
Metabolic acidosis is BEST treated with:
Potassium chloride
Sodium bicarbonate
Calcium gluconate
Dextrose
Question 23
The DOC for malignant hyperthermia is:
Diazepam
Phenytoin
Dantrolene
Naloxone
Question 24
Odd-man out: Which is not a synonym of NaHCO3?
Baking soda
Sal de vichy
Sodium acid bicarbonate
Soda saleratus
Question 25
Odd-man out: Which is not a synonym of NaHCO3?
Baking soda
Sal de vichy
Sodium acid bicarbonate
Soda saleratus
Question 26
Thiamine is also commonly known as:
Vitamin B1
Vitamin B3
Vitamin B6
Vitamin B12
Question 27
Dr. Ramona “Ramsy” Samaniegera, a usually composed clinician, was evaluated after suddenly looking too inspired.
Vital signs revealed a temperature of 104°F, a heart rate of 134 bpm doing cardio without consent. Her respiratory rate at 18 breaths/min, pretending nothing was wrong, while her blood pressure with 142/96 mm Hg, indicating stress had officially joined the chat.
Evaluate the vital signs of Ramona.
Hypothermia with bradycardia and hypotension
Hyperthermia with tachycardia and Stage I HTN
Hyperthermia with respiratory distress and hypotension
Hypothermia with bradycardia and Pre-HTN